Covance's Biotechnology Division in Harrogate, North Yorkshire is hiring Experimental Officers at all experience levels. Recent major investments have been made in facilities on the Harrogate site and successful candidates will be part of our exciting and expanding future, working with progressive management, inventive technologies and alongside other talented scientists.
The Biotechnology Division is a fully GMP/GLP/GCP compliant facility providing a comprehensive portfolio of services including GMP cell bank production and storage, cell bank and viral vector safety testing, viral clearance services, cell based bioassays, biodistribution studies, analysis of biofluids using immunochemistry based techniques and extensive protein chemistry support including cGMP batch release and stability testing.
Experimental Officers are laboratory based analysts who are responsible for performing a wide variety of assays within a regulatory compliant laboratory. Due to the varied nature of the scientific work involved, candidates must be able to demonstrate a flexible approach to laboratory work, possess excellent communication and time management skills and be able to maintain a high standard of record keeping.
The Biopotency section is focused on the assessment of the biological activity of large molecules using cell-based assays. The accurate determination of the potency of a drug is necessary to release manufactured batches of the drug, assess stability (shelf life) and evaluate the impact of changes in manufacturing process or in formulation. Cell-based assays are also used as part of the immunogenicity assessment of the drug to detect the presence of neutralising anti-drug antibodies in toxicology and clinical trials. A wide variety of cellular, biochemical and ligand/receptor binding assays are used. The endpoint determinations of these assays include, but are not limited to; Fluorescence, Luminescence, ELISA, Flow cytometry, electrochemiluminescence (MSD) and FRET.
Candidates will be considered from a range of backgrounds; Bachelors/Masters degree, or those with industrial experience would be considered appropriate for the position. Candidates are expected to have a background in the life sciences area and should ideally possess practical experience of a relevant subject. A sound working knowledge of 'Good Laboratory Practice' and 'Good Manufacturing Practice' would be advantageous.
Experienced individuals would be expected to support a more technical orientated or management focused role.
There are excellent promotion prospects and positions are available at all levels depending on qualifications and experience.
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